Clinical characteristics of 50466 hospitalized patients with 2019‐nCoV infection
Objective
We aim to summarize reliable evidences of evidence‐based medicine for the treatment and prevention of the 2019 novel coronavirus (2019‐nCoV) by analyzing all the published studies on the clinical characteristics of patients with 2019‐nCoV.
Methods
PubMed, Cochrane Library, Embase, and other databases were searched. Several studies on the clinical characteristics of 2019‐nCoV infection were collected for Meta‐analysis.
Results
Ten studies were included in Meta‐analysis, including a total number of 50466 patients with 2019‐nCoV infection. Meta‐analysis shows that, among these patients, the incidence of fever was 89.1%, the incidence of cough was 72.2%, and the incidence of muscle soreness or fatigue was 42.5%. The incidence of acute respiratory distress syndrome (ARDS) was 14.8%, the incidence of abnormal chest computer tomography (CT) was 96.6%, the percentage of severe cases in all infected cases was 18.1%, and the case fatality rate of patients with 2019‐nCoV infection was 4.3%.
Conclusion
Fever and cough are the most common symptoms in patients with 2019‐nCoV infection, and most of these patients have abnormal chest CT examination. Several people have muscle soreness or fatigue as well as ARDS. Diarrhea, hemoptysis, headache, sore throat, shock, and other symptoms only occur in a small number of patients. The case fatality rate of patients with 2019‐nCoV infection is lower than that of Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS).
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Publisher URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.25735
Open URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jmv.25735
DOI: 10.1002/jmv.25735
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